BACKGROUND:   A   combination   of   horizontal   and   vertical   third   molar  impaction   is   a  rareoccurrence.When  the  tooth  is  unable to  erupt  to  its  proper  position  and  fail  to achieve  a  normalocclusion, it is known as impacted tooth. CASE DETAILS: In this scientific article,   case report of a female patient aged 30 years reported with acombination of horizontally and  vertically impacted third molars in the maxilla and mandible has beenpresented.  The  treatment  included  surgical  removal  of  the  impacted  teeth  without  any  damage  tounderlying structures. CONCLUSION: Horizontal  impaction of left maxillary third molar,vertical impaction of  right maxillarythird molar and left mandibular third molar is a rare occurrence. If symptomatic, surgical removal has tobe planned as earlier as possible rather than late complications.