ABSTRACT BACKGROUND፡ Gilbert syndrome is a well-recognized condition causing unconjugated hyperbilirubinemia  with otherwise  normal transaminases and liver function tests.  CASE: A 21 year old male patient presented with recurrent episodes of jaundice  over four years. The episodes were preceded by stressful conditions and intercurrent illnesses. All laboratory prameters were normal except an unconjugated hyperbilirubinemia.  A diagnosis of Gilbert syndrome was made after careful clinical evaluation.   CONCLUSION: Recognizing Gilbert syndrome has important clinical implicaitions by avoiding uncessary and expensive workup of patients with jaundice. Mangement entails avoiding stressful conditions and prolonged fasting.KEYWORDS: Gilbert Syndrome, Jaundice, Hyperbillirubinemia, Liver, Ethiopia